Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells | Zendy

Hong Yu Zhang | Zendy; Li Li | Zendy; Qian Dong | Zendy; Yufeng Wang | Zendy; Qiaoling Feng | Zendy; Xinying Ou | Zendy; Pengfei Zhou | Zendy; TongChuan He | Zendy; Jinyong Luo | Zendy

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Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells

Author(s) -

Hong Yu Zhang,

Li Li,

Qian Dong,

Yufeng Wang,

Qiaoling Feng,

Xinying Ou,

Pengfei Zhou,

TongChuan He,

Jinyong Luo

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430376

Subject(s) - creb , runx2 , phosphorylation , microbiology and biotechnology , mesenchymal stem cell , signal transduction , chemistry , protein kinase a , osteocalcin , osteopontin , alkaline phosphatase , transcription factor , biology , endocrinology , biochemistry , enzyme , gene

BMP9 is highly capable of promoting osteogenic differentiation of mesenchymal stem cells (MSCs) although the molecular mechanism involved is largely unknown. Here, we explored the detail role of PKA/CREB signaling in BMP9-induced osteogenic differentiation.

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