Psychological Stress-Derived Prolactin Modulates Occludin Expression in Vaginal Epithelial Cells to Compromise Barrier Function
Author(s) -
Xueyan Li,
Xiaowei Liu,
Yu Song
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430341
Subject(s) - occludin , tight junction , barrier function , chromatin immunoprecipitation , prolactin , microbiology and biotechnology , biology , blot , western blot , endocrinology , medicine , chemistry , gene expression , hormone , biochemistry , promoter , gene
The causative factors of the vaginitis are not fully understood yet. Epithelial barrier dysfunction plays a critical role in the pathogenesis of vaginitis. This study aims to investigate the role of prolactin (PRL) in the causing the vaginal epithelial barrier dysfunction.
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