Effects of Astragaloside IV Against the TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Peritoneal Mesothelial Cells by Promoting Smad 7 Expression | Zendy

Lu Zhang | Zendy; Zhenghong Li | Zendy; Weiming He | Zendy; Ling-Dong Xu | Zendy; Jing Wang | Zendy; Jun Shi | Zendy; Meixiao Sheng | Zendy

Open Access

Effects of Astragaloside IV Against the TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Peritoneal Mesothelial Cells by Promoting Smad 7 Expression

Author(s) -

Lu Zhang,

Zhenghong Li,

Weiming He,

Ling-Dong Xu,

Jing Wang,

Jun Shi,

Meixiao Sheng

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430332

Subject(s) - epithelial–mesenchymal transition , smad , vimentin , chemistry , transforming growth factor , mesothelial cell , western blot , cancer research , gene knockdown , downregulation and upregulation , signal transduction , microbiology and biotechnology , biology , immunology , medicine , pathology , immunohistochemistry , apoptosis , biochemistry , gene

To investigate the effect of Astragaloside IV (AS-IV) on the regulation of the TGF-β1/Smad signaling pathway in peritoneal mesothelial cells with an epithelial-to-mesenchymal transition (EMT).

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