Propofol Prevents Renal Ischemia-Reperfusion Injury via Inhibiting the Oxidative Stress Pathways
Author(s) -
Yingjie Li,
Dandan Zhong,
Lei Lei,
Yingli Jia,
Hong Zhou,
Baoxue Yang
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430329
Subject(s) - propofol , medicine , apoptosis , chop , kidney , pharmacology , oxidative stress , western blot , ischemia , renal function , reperfusion injury , renal ischemia , transplantation , caspase 3 , endocrinology , chemistry , programmed cell death , biochemistry , chemotherapy , gene
Renal ischemia/reperfusion injury (IRI) is a risk for acute renal failure and delayed graft function in renal transplantation and cardiac surgery. The purpose of this study is to determine whether propofol could attenuate renal IRI and explore related mechanism.
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