Functional Network Analysis Reveals Versatile MicroRNAs in Human Heart
Author(s) -
Yingqi Xu,
Wenliang Zhu,
Yong Sun,
Zhe Wang,
Wei Yuan,
Zhimin Du
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430324
Subject(s) - microrna , heart failure , myocardial infarction , computational biology , bioinformatics , gene regulatory network , regulation of gene expression , medicine , gene expression , biology , gene , genetics
Acting on many mRNAs allows the power of a single miRNA to modulate multiple pathophysiological phenotypes. One question is whether versatile miRNAs exist in the pathological scenarios of myocardial infarction (MI) and heart failure (HF).
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