Open AccessMiR-499 Enhances the Cisplatin Sensitivity of Esophageal Carcinoma Cell Lines by Targeting DNA Polymerase β
Author(s) -
Yuanyuan Wang,
Jianfang Feng,
Wenqiao Zang,
Yuwen Du,
Xiaonan Chen,
Qianqian Sun,
Ziming Dong,
Guoqiang Zhao
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430321
Subject(s) - cisplatin , apoptosis , cancer research , flow cytometry , cell growth , cell culture , microbiology and biotechnology , biology , chemistry , chemotherapy , biochemistry , genetics
Human DNA polymerase β (DNA polymerase β, polβ) is a small monomeric protein essential for short-patch base excision repair (BER). It plays an important role in regulating the sensitivity of tumor cells to chemotherapy.
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