Hydrogen Sulfide Inhalation Improves Neurological Outcome via NF-κB-Mediated Inflammatory Pathway in a Rat Model of Cardiac Arrest and Resuscitation | Zendy

Wei Xia | Zendy; Bing Zhang | Zendy; Yu Zhang | Zendy; Hangbing Li | Zendy; Long Cheng | Zendy; Xiajie Zhao | Zendy; Jinling Yin | Zendy; Guonian Wang | Zendy

Open Access

Hydrogen Sulfide Inhalation Improves Neurological Outcome via NF-κB-Mediated Inflammatory Pathway in a Rat Model of Cardiac Arrest and Resuscitation

Author(s) -

Wei Xia,

Bing Zhang,

Yu Zhang,

Hangbing Li,

Long Cheng,

Xiajie Zhao,

Jinling Yin,

Guonian Wang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430316

Subject(s) - proinflammatory cytokine , inhalation , medicine , ventricular fibrillation , myeloperoxidase , inflammation , anesthesia , resuscitation , tumor necrosis factor alpha , pharmacology , immunology

The effects of H2S on cerebral inflammatory reaction after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) remain poorly understood. In this study, we investigated the effects of exogenous 40 ppm and 80 ppm H2S gas on inflammatory reaction and neurological outcome after CA/CPR.

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