MiR-323 Inhibits Prostate Cancer Vascularization Through Adiponectin Receptor | Zendy

Qiruo Gao | Zendy; Xudong Yao | Zendy; Junhua Zheng | Zendy

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MiR-323 Inhibits Prostate Cancer Vascularization Through Adiponectin Receptor

Author(s) -

Qiruo Gao,

Xudong Yao,

Junhua Zheng

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430313

Subject(s) - adiponectin receptor 1 , adiponectin , umbilical vein , ampk , vascular endothelial growth factor , messenger rna , endocrinology , receptor , medicine , chemistry , microrna , cancer research , vegf receptors , protein kinase a , kinase , obesity , insulin resistance , biochemistry , in vitro , gene

The current treatments fail to provide satisfactory cure for aggressive prostate cancers (PCs). Hence, further comprehension of PC metastasis is highly appreciated for improving the levels of therapy. We have previously shown that Adiponectin reduces the levels of vascular endothelial growth factor A (VEGF-A) in PCs to suppress tumor-associated neovascularization, possibly through AMPK/mTor signaling. Here, we studied the regulation of Adiponectin signaling in PCs.

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