Open AccessCaveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway
Author(s) -
Wenqing Tang,
Xuemei Feng,
Si Zhang,
Zhenggang Ren,
Yinkun Liu,
Biwei Yang,
Bei Lv,
YuDong Cai,
Jinglin Xia,
Ningling Ge
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430292
Subject(s) - anoikis , internalization , gene knockdown , caveolae , cancer research , mapk/erk pathway , caveolin 1 , microbiology and biotechnology , protein kinase b , biology , pi3k/akt/mtor pathway , signal transduction , chemistry , apoptosis , programmed cell death , genetics , cell
Anoikis resistance is a prerequisite for hepatocellular carcinoma (HCC) metastasis. The role of Caveolin-1 (CAV1) in anoikis resistance of HCC remains unclear.
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