Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS | Zendy

Hongmei Li | Zendy; Lei Han | Zendy; ZhiLing Yang | Zendy; Wei Huang | Zendy; Xin Zhang | Zendy; Yan Gu | Zendy; Yinfeng Li | Zendy; Xiaojie Liu | Zendy; Lijuan Zhou | Zendy; Jiongyu Hu | Zendy; Meijia Yu | Zendy; Jing Yang | Zendy; Yilin Li | Zendy; Yingru Zheng | Zendy; Jianxin Guo | Zendy; Jian Han | Zendy; Li Li | Zendy

Open Access

Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS

Author(s) -

Hongmei Li,

Lei Han,

ZhiLing Yang,

Wei Huang,

Xin Zhang,

Yan Gu,

Yinfeng Li,

Xiaojie Liu,

Lijuan Zhou,

Jiongyu Hu,

Meijia Yu,

Jing Yang,

Yilin Li,

Yingru Zheng,

Jianxin Guo,

Jian Han,

Li Li

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430283

Subject(s) - syncytiotrophoblast , biology , western blot , proteome , microbiology and biotechnology , proteomics , biochemistry , placenta , gene , genetics , fetus , pregnancy

Previous studies have revealed that the increased shedding of syncytiotrophoblast extracellular vesicles (STBM) may lead to preeclampsia (PE). We aimed to identify the proteins carried by STBM and their potential pathological roles in early-onset severe PE.

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