MiR-22 Suppresses BMP7 in the Development of Cirrhosis | Zendy

Dong Ji | Zendy; Bing Li | Zendy; Qing Shao | Zendy; Fan Li | Zendy; Zhongbin Li | Zendy; Guofeng Chen | Zendy

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MiR-22 Suppresses BMP7 in the Development of Cirrhosis

Author(s) -

Dong Ji,

Bing Li,

Qing Shao,

Fan Li,

Zhongbin Li,

Guofeng Chen

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430276

Subject(s) - cirrhosis , bone morphogenetic protein 7 , microrna , mir 122 , downregulation and upregulation , ccl4 , cancer research , medicine , pathogenesis , biology , endocrinology , microbiology and biotechnology , carbon tetrachloride , chemistry , bone morphogenetic protein , gene , biochemistry , organic chemistry

New strategies for the prevention and treatment of cirrhosis are urgently needed for improving therapeutic outcome. A role of microRNAs (miRNAs) in the pathogenesis of cirrhosis has been recently acknowledged, whereas the exact involved miRNAs as well as the associated molecular signaling pathways have not been determined. Specifically, the studies on the relationship between miR-22 and bone morphogenic protein 7 (BMP7) in the development of cirrhosis are lacking.

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