Curcumin Protects -SH Groups and Sulphate Transport after Oxidative Damage in Human Erythrocytes
Author(s) -
Rossana Morabito,
Giuseppe Falliti,
Antonella Geraci,
Giuseppina La Spada,
Angela Marino
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430256
Subject(s) - curcumin , oxidative stress , band 3 , chemistry , oxidative phosphorylation , membrane , biophysics , antioxidant , biochemistry , red blood cell , reactive oxygen species , cell membrane , membrane protein , biology
Erythrocytes, continuously exposed to oxygen pressure and toxic compounds, are sensitive to oxidative stress, namely acting on integral Band 3 protein, with consequences on cell membranes deformability and anion transport efficiency. The aim of the present investigation, conducted on human erythrocytes, is to verify whether curcumin (1 or 10µM), a natural compound with proved antioxidant properties, may counteract Band 3-mediated anion transport alterations due to oxidative stress.
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