MiRNAs Associated Polymorphisms in the 3'UTR of MET Promote the Risk of Non-Small Cell Lung Cancer | Zendy

Xiaojue Zhu | Zendy; Changqing Fu | Zendy; Lihua Zhang | Zendy; Guoxing Xu | Zendy; Shusheng Wang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

MiRNAs Associated Polymorphisms in the 3'UTR of MET Promote the Risk of Non-Small Cell Lung Cancer

Author(s) -

Xiaojue Zhu,

Changqing Fu,

Lihua Zhang,

Guoxing Xu,

Shusheng Wang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430239

Subject(s) - three prime untranslated region , microrna , carcinogenesis , lung cancer , genotype , single nucleotide polymorphism , biology , oncogene , cancer research , untranslated region , snp , oncology , metastasis , cancer , genetics , medicine , gene , cell cycle , messenger rna

MET can act as an oncogene and its signaling server has essential roles in regulating tumorigenesis. Polymorphisms in MET have been reported to be associated with poor prognosis in human cancer, but an association with the risk of human non-small-cell lung cancer (NSCLC) has not been found so far. In this study rs41281081 and rs76322625, located in the 3'UTR of MET, were selected to evaluate their relationship with the risk of NSCLC among the Chinese population.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research