Sox9 Activation is Essential for the Recovery of Lung Function after Acute Lung Injury | Zendy

Lei Li | Zendy; Hong Zhang | Zendy; Min Dong | Zendy; RuYuan Zhang | Zendy; Jun Wu | Zendy; Hongping Qu | Zendy; Yaoqing Tang | Zendy

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Sox9 Activation is Essential for the Recovery of Lung Function after Acute Lung Injury

Author(s) -

Lei Li,

Hong Zhang,

Min Dong,

RuYuan Zhang,

Jun Wu,

Hongping Qu,

Yaoqing Tang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430236

Subject(s) - lung , sox9 , medicine , ards , western blot , pathogenesis , diffuse alveolar damage , pathology , andrology , cancer research , immunology , biology , gene expression , acute respiratory distress , gene , biochemistry

Acute lung injury (ALI) often predisposes acute respiratory distress syndrome (ARDS) in humans, and is featured with neutrophilic alveolitis, injury of the alveolar epithelium and endothelium, hyaline membrane formation, and microvascular thrombi. Although the pathogenesis of ALI is relatively well studied, the knowledge on the molecular regulation of the post-ALI lung recovery are poorly understood.

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