Enhanced Eryptosis Following Auranofin Exposure | Zendy

Kousi Alzoubi | Zendy; Jasmin Egler | Zendy; Majed Abed | Zendy; Florian Läng | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Enhanced Eryptosis Following Auranofin Exposure

Author(s) -

Kousi Alzoubi,

Jasmin Egler,

Majed Abed,

Florian Läng

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430228

Subject(s) - auranofin , phosphatidylserine , oxidative stress , reactive oxygen species , apoptosis , chemistry , annexin a5 , pharmacology , cytosol , biophysics , programmed cell death , annexin , microbiology and biotechnology , biochemistry , phospholipid , biology , membrane , immunology , rheumatoid arthritis , enzyme

The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia. At least in theory the anaemia could result from stimulation of suicidal death of erythrocytes or eryptosis, which involves cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research