Open AccessMipu1 Inhibits Lipid Accumulation Through Down-Regulation of CD36 in RAW264.7 Cells
Author(s) -
Shunlin Qu,
Wenjing Fan,
Chi Zhang,
Fang Guo,
Wenjun Pan,
Dan Han,
Wěi Li,
Yu-Ning Zhu,
Zhisheng Jiang
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430215
Subject(s) - cd36 , chromatin immunoprecipitation , western blot , chemistry , microbiology and biotechnology , luciferase , immunoprecipitation , promoter , transfection , biochemistry , biology , gene expression , gene
Our recent data indicated that Mipu1 overexpression reduces lipid intake and CD36 expression of macrophages in the presence of oxLDL. However, the mechanism of Mipu1 inhibiting lipid accumulation in macrophages is not elucidated.
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