Eruberin A, a Natural Flavanol Glycoside, Exerts Anti-Fibrotic Action on Pancreatic Stellate Cells | Zendy

Siu Wai Tsang | Zendy; Hongjie Zhang | Zendy; Yegao Chen | Zendy; Kathy K. W. Au-Yeung | Zendy; Zhaoxiang Bian | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Eruberin A, a Natural Flavanol Glycoside, Exerts Anti-Fibrotic Action on Pancreatic Stellate Cells

Author(s) -

Siu Wai Tsang,

Hongjie Zhang,

Yegao Chen,

Kathy K. W. Au-Yeung,

Zhaoxiang Bian

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430204

Subject(s) - hepatic stellate cell , protein kinase b , pi3k/akt/mtor pathway , signal transduction , phosphorylation , fibronectin , cancer research , microbiology and biotechnology , endocrinology , chemistry , biology , medicine , extracellular matrix

Eruberin A (2, 3-dehydroflavonoid), a flavanol glycoside isolated from Pronephrium penangianum, has been used as a blood-nourishing folk medicine for centuries; however, it indeed possesses a variety of other health-promoting benefits including anti-fibrotic bioactivity. Activation of pancreatic stellate cells (PSCs) is the key initiating step in pancreatic fibrosis, which is a characteristic feature associated with chronic pancreatitis and pancreatic adenocarcinoma.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research