The Roles of p38 MAPK and ERK1/2 in Coplanar Polychlorinated Biphenyls-Induced Apoptosis of Human Extravillous Cytotrophoblast-Derived Transformed Cells
Author(s) -
Liu Zhu,
Hongjie Ruan,
Pingqing Gu,
Wenyan Ding,
Xiaohui Luo,
Rong Huang,
Wei Zhao,
Ling-juan Gao
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430203
Subject(s) - mapk/erk pathway , p38 mitogen activated protein kinases , apoptosis , microbiology and biotechnology , signal transduction , kinase , western blot , biology , protein kinase a , chemistry , biochemistry , gene
The purpose of this study was to investigate the relationships among exposure to coplanar polychlorinated biphenyls (Co-PCBs), the expression of gC1qR and the underlying intracellular apoptotic signaling pathways of human extravillous cytotrophoblast (EVCT)-derived transformed cells (HTR-8/SVneo and HPT-8).
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