Circulating Hepatocellular Carcinoma Cells are Characterized by CXCR4 and MMP26 | Zendy

Yu Chang | Zendy; Zhiting Wang | Zendy; Xiaomei Xu | Zendy; Wei Xiang | Zendy; Xiaoying Huang | Zendy

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Circulating Hepatocellular Carcinoma Cells are Characterized by CXCR4 and MMP26

Author(s) -

Yu Chang,

Zhiting Wang,

Xiaomei Xu,

Wei Xiang,

Xiaoying Huang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430201

Subject(s) - cxcr4 , circulating tumor cell , metastasis , hepatocellular carcinoma , cancer research , medicine , primary tumor , transplantation , cancer , cancer cell , pathology , receptor , chemokine

Primary hepatocellular carcinoma (HCC) is highly invasive, and often results in an early distal metastasis resulting in poor prognosis and therapeutic outcome. Cancer cells disseminating from the tumor and entering circulation are termed circulating tumor cells (CTCs). Although substantial progress has been made to identify those CTCs in HCC, no good marker (cocktail) has so far been identified.

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