Interleukin-1β Promotes Epithelial-Derived Alveolar Elastogenesis via αvβ6 Integrin-Dependent TGF-β Activation | Zendy

Jiarong Wang | Zendy; Lei Bao | Zendy; Benli Yu | Zendy; Zhaoyun Liu | Zendy; Wenli Han | Zendy; Chun Deng | Zendy; Chunbao Guo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Interleukin-1β Promotes Epithelial-Derived Alveolar Elastogenesis via αvβ6 Integrin-Dependent TGF-β Activation

Author(s) -

Jiarong Wang,

Lei Bao,

Benli Yu,

Zhaoyun Liu,

Wenli Han,

Chun Deng,

Chunbao Guo

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430185

Subject(s) - elastin , hyperoxia , immunostaining , transforming growth factor , chemistry , downregulation and upregulation , bronchopulmonary dysplasia , mesenchymal stem cell , lung , epithelial–mesenchymal transition , transforming growth factor beta , microbiology and biotechnology , vimentin , pathology , immunohistochemistry , cancer research , biology , medicine , biochemistry , pregnancy , genetics , gene , gestational age

IL-1β creates persistent pulmonary inflammation accompanied by elevated transforming growth factor β (TGF-β levels and is associated with abnormal elastogenesis, which is observed in bronchopulmonary dysplasia (BPD). Although progress has been made in this field, the mechanisms underlying this process remain only partially understood.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research