Open AccessTempol, a Superoxide Dismutase-Mimetic Drug, Ameliorates Progression of Renal Disease in CKD Mice
Author(s) -
Wei Ding,
Bin Wang,
Minmin Zhang,
Yong Gu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430183
Subject(s) - superoxide dismutase , drug , pharmacology , medicine , kidney disease , disease , oxidative stress , reactive oxygen species , chemistry , biochemistry
Oxidative stress has been implicated in the pathogenesis of chronic kidney disease (CKD) and antioxidants may ameliorate disease progression. We investigate the beneficial effect of Tempol, a superoxide dismutase-mimetic drug, on progression of disease in a mouse model of CKD.
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