Cordyceps Militaris Alleviates Severity of Murine Acute Lung Injury Through miRNAs-Mediated CXCR2 Inhibition | Zendy

Sheng Liu | Zendy; Jian Tang | Zendy; Lei Huang | Zendy; Qirong Xu | Zendy; Xiang Ling | Zendy; Jichun Liu | Zendy

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Cordyceps Militaris Alleviates Severity of Murine Acute Lung Injury Through miRNAs-Mediated CXCR2 Inhibition

Author(s) -

Sheng Liu,

Jian Tang,

Lei Huang,

Qirong Xu,

Xiang Ling,

Jichun Liu

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430168

Subject(s) - cordyceps militaris , bleomycin , medicine , ards , lung , cxcl1 , immunology , pharmacology , biology , inflammation , chemokine , traditional medicine , chemotherapy , cordyceps

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are lethal diseases in humans, and the current treatments have limited therapeutic effects. Cordyceps militaris (CM) is a caterpillar-grown traditional medicinal mushroom, and has been used as a natural invigorant for longevity, endurance, and vitality in China. Recently, purified extracts from CM have been shown to have beneficial effects on various diseases including cancer. Nevertheless, a role of CM in ALI has not been examined previously.

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