The Role of MicroRNA-381 in Chondrogenesis and Interleukin-1-β Induced Chondrocyte Responses
Author(s) -
Changhe Hou,
Fangang Meng,
Zhiqi Zhang,
Yan Kang,
Weishen Chen,
Guangxin Huang,
Ming Fu,
Puyi Sheng,
Ziji Zhang,
WeiMing Liao
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430148
Subject(s) - chondrogenesis , cartilage , chondrocyte , sox9 , microbiology and biotechnology , chemistry , microrna , runx2 , type ii collagen , small interfering rna , gene expression , biology , transfection , anatomy , biochemistry , gene
The molecular pathways regulating cartilage degradation are unclear. miR-381 was identified as a putative regulator of chondrogenesis related genes. Here, we examined its role in chondrogenesis and osteoarthritic cartilage degeneration.
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