Ovarian Germline Stem Cells (OGSCs) and the Hippo Signaling Pathway Association with Physiological and Pathological Ovarian Aging in Mice | Zendy

Jia Li | Zendy; Fangyue Zhou | Zendy; Tuochen Zheng | Zendy; Zezheng Pan | Zendy; Xia Liang | Zendy; Jian Huang | Zendy; Liping Zheng | Zendy; Yuehui Zheng | Zendy

Open Access

Ovarian Germline Stem Cells (OGSCs) and the Hippo Signaling Pathway Association with Physiological and Pathological Ovarian Aging in Mice

Author(s) -

Jia Li,

Fangyue Zhou,

Tuochen Zheng,

Zezheng Pan,

Xia Liang,

Jian Huang,

Liping Zheng,

Yuehui Zheng

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430144

Subject(s) - hippo signaling pathway , biology , yap1 , stem cell , ovarian cortex , ovary , immunohistochemistry , ovarian follicle , noggin , signal transduction , microbiology and biotechnology , medicine , andrology , cancer research , endocrinology , gene , immunology , transcription factor , genetics , ovarian tissue , bone morphogenetic protein

The Hippo signaling pathway plays fundamental roles in stem cell maintenance in a variety of tissues and has thus implications for stem cell biology. Key components of this recently discovered pathway have been shown to be associated with primordial follicle activation. However, whether the Hippo signaling pathway plays a role in the development of Ovarian Germline Stem Cells (OGSCs) during physiological and pathological ovarian aging in mice is unknown.

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