MMP13 Regulates Aggressiveness of Pediatric Multiple Myeloma Through VEGF-C | Zendy

Lingyun Xu | Zendy; Kai Sun | Zendy; Min Xia | Zendy; Xiaoli Li | Zendy; Lu YanMing | Zendy

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MMP13 Regulates Aggressiveness of Pediatric Multiple Myeloma Through VEGF-C

Author(s) -

Lingyun Xu,

Kai Sun,

Min Xia,

Xiaoli Li,

Lu YanMing

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430116

Subject(s) - lymphatic system , vascular endothelial growth factor c , lymphangiogenesis , protein kinase b , pi3k/akt/mtor pathway , cancer research , medicine , lymph node , vascular endothelial growth factor , lymph , vegf receptors , endocrinology , vascular endothelial growth factor a , signal transduction , metastasis , pathology , cancer , microbiology and biotechnology , biology

Even though the blood and lymphatic vascular systems are both involved in the occurrence of cancer metastases, it is believed that lymphatic system is primarily responsible for the initial metastasis. Nevertheless, the molecular mechanisms underlying lymphangiogenesis of multiple myeloma (MM), especially in pediatric period, have not been clarified.

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