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Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study
Author(s) -
Beatrice Engelmann,
Julia Bischof,
A.-L. Dirk,
Nele Friedrich,
Elke Hammer,
Thomas Thiele,
Dagmar Führer,
Georg Homuth,
Georg Brabant,
Uwe Völker
Publication year - 2015
Publication title -
european thyroid journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.23
H-Index - 10
eISSN - 2235-0802
pISSN - 2235-0640
DOI - 10.1159/000381769
Subject(s) - medicine , thyroid , endocrinology , proteomics , blood proteins , hormone , coagulation , pathogenesis , biology , biochemistry , gene
Hyperthyroidism is known to induce a hypercoagulable state. It stimulates plasma levels of procoagulative factors and reduces fibrinolytic activity. So far most of the data have been derived from patients with endogenous hyperthyroidism with a wide variability in the underlying pathogenesis and severity of the disease.

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