Open AccessThe Genetics of IgA Nephropathy: An Overview from Western Countries
Author(s) -
John Feehally,
Jonathan Barratt
Publication year - 2015
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000381738
Subject(s) - disease , nephropathy , glomerulonephritis , epigenetics , immunology , phenotype , biology , kidney disease , epidemiology , genetics , medicine , gene , pathology , kidney , diabetes mellitus , endocrinology
IgA nephropathy (IgAN) is the commonest primary glomerulonephritis worldwide and a significant cause of chronic kidney disease and end-stage renal disease. It is widely accepted that genetic factors play a role in the pathogenesis of IgAN. However, the identity of these genetic factors remains uncertain.
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