A Novel Multipeptide Microarray for the Specific and Sensitive Mapping of Linear IgE-Binding Epitopes of Food Allergens | Zendy

Yvonne Kühne | Zendy; Gerald Reese | Zendy; Barbara BallmerWeber | Zendy; B. Niggemann | Zendy; Kay-Martin Hanschmann | Zendy; Stefan Vieths | Zendy; Thomas Holzhauser | Zendy

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A Novel Multipeptide Microarray for the Specific and Sensitive Mapping of Linear IgE-Binding Epitopes of Food Allergens

Author(s) -

Yvonne Kühne,

Gerald Reese,

Barbara BallmerWeber,

B. Niggemann,

Kay-Martin Hanschmann,

Stefan Vieths,

Thomas Holzhauser

Publication year - 2015

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000381344

Subject(s) - epitope , immunoglobulin e , allergen , microarray , microbiology and biotechnology , chemistry , food allergy , peptide , biology , immunology , allergy , biochemistry , antibody , gene , gene expression

The identification of B-cell epitopes of food allergens can possibly lead to novel diagnostic tools and therapeutic reagents for food allergy. We sought to develop a flexible, low-tech, cost-effective and reproducible multipeptide microarray for the research environment to enable large-scale screening of IgE epitopes of food allergens.

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