The Histamine H4 Receptor Regulates Chemokine Production in Human Natural Killer Cells | Zendy

Susanne Mommert | Zendy; Oliver DittrichBreiholz | Zendy; Holger Stark | Zendy; Ralf Gutzmer | Zendy; Thomas Werfel | Zendy

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The Histamine H4 Receptor Regulates Chemokine Production in Human Natural Killer Cells

Author(s) -

Susanne Mommert,

Oliver DittrichBreiholz,

Holger Stark,

Ralf Gutzmer,

Thomas Werfel

Publication year - 2015

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000381340

Subject(s) - immunology , histamine , histamine h4 receptor , chemokine , chemokine receptor , ccl13 , biology , receptor , histamine h2 receptor , inflammation , endocrinology , biochemistry , antagonist

Natural killer (NK) cells have been detected in the lesional skin of patients with inflammatory skin diseases, where high levels of histamine are also present. Therefore, we investigated the effect of histamine, in particular via the histamine H4 receptor (H4R), on gene expression levels in human NK cells.

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