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A Small Region of Porcine Hemagglutinating Encephalomyelitis Virus Spike Protein Interacts with the Neural Cell Adhesion Molecule
Author(s) -
Bo Dong,
Wei Gao,
Huijun Lu,
Kui Zhao,
Ning Ding,
Wenfeng Liu,
Jiakuan Zhao,
Yungang Lan,
Bo Tang,
Jin Zhao,
Wenqi He,
Feng Gao
Publication year - 2015
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000381060
Subject(s) - neural cell adhesion molecule , fusion protein , gene , microbiology and biotechnology , biology , two hybrid screening , protein subunit , chemistry , recombinant dna , cell adhesion , biochemistry , cell
The spike (S) protein of porcine hemagglutinating encephalomyelitis virus (PHEV) may mediate infection by binding to a cellular neural cell adhesion molecule (NCAM). This study aimed to identify the crucial domain of the S1 subunit of the S protein that interacts with NCAM.

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