Efficacy and Safety of Sublingual Immunotherapy for Two Seasons in Patients with Japanese Cedar Pollinosis | Zendy

Yoshitaka Okamoto | Zendy; Kimihiro Okubo | Zendy; Syuji Yonekura | Zendy; Kazuhiro Hashiguchi | Zendy; Minoru Goto | Zendy; Takashi Otsuka | Zendy; Tadayuki Murata | Zendy; Yûji Nakao | Zendy; Chigiri Kanazawa | Zendy; H. Nagakura | Zendy; Toru Okawa | Zendy; Kōichi Nakano | Zendy; Minako Hisamitsu | Zendy; Shinya Kaneko | Zendy; Akiyoshi Konno | Zendy

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Efficacy and Safety of Sublingual Immunotherapy for Two Seasons in Patients with Japanese Cedar Pollinosis

Author(s) -

Yoshitaka Okamoto,

Kimihiro Okubo,

Syuji Yonekura,

Kazuhiro Hashiguchi,

Minoru Goto,

Takashi Otsuka,

Tadayuki Murata,

Yûji Nakao,

Chigiri Kanazawa,

H. Nagakura,

Toru Okawa,

Kōichi Nakano,

Minako Hisamitsu,

Shinya Kaneko,

Akiyoshi Konno

Publication year - 2015

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000381059

Subject(s) - medicine , placebo , sublingual immunotherapy , sublingual administration , allergy , slit , randomized controlled trial , clinical endpoint , gastroenterology , immunology , allergen , pathology , alternative medicine , biology , genetics

Japanese cedar (JC) pollinosis is the most common seasonal allergic rhinitis in Japan. Standardized JC pollen extract is available for subcutaneous immunotherapy, but this treatment is limited by potentially serious side effects. The aim of this double-blind, randomized comparative study was to evaluate the efficacy and safety of standardized JC pollen extract in a new oral formulation (CEDARTOLEN®, Torii Pharmaceutical Co., Ltd., Tokyo, Japan) for sublingual immunotherapy (SLIT) for JC pollinosis.

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