Open Access<b><i>FOXO3:</i></b> A Major Gene for Human Longevity - A Mini-Review
Author(s) -
Brian J. Morris,
D. Craig Willcox,
Timothy A. Donlon,
Bradley J. Willcox
Publication year - 2015
Publication title -
gerontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.397
H-Index - 94
eISSN - 1423-0003
pISSN - 0304-324X
DOI - 10.1159/000375235
Subject(s) - foxo3 , longevity , proteostasis , biology , transcription factor , genetics , gene
The gene FOXO3, encoding the transcription factor forkhead box O-3 (FoxO3), is one of only two for which genetic polymorphisms have exhibited consistent associations with longevity in diverse human populations.
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