Autophagy Protects Renal Tubular Cells Against Ischemia / Reperfusion Injury in a Time-Dependent Manner | Zendy

Xuejing Guan | Zendy; Yingying Qian | Zendy; Yue Shen | Zendy; Lulu Zhang | Zendy; Yi Du | Zendy; Huili Dai | Zendy; Jiaqi Qian | Zendy; Yucheng Yan | Zendy

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Autophagy Protects Renal Tubular Cells Against Ischemia / Reperfusion Injury in a Time-Dependent Manner

Author(s) -

Xuejing Guan,

Yingying Qian,

Yue Shen,

Lulu Zhang,

Yi Du,

Huili Dai,

Jiaqi Qian,

Yucheng Yan

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000374071

Subject(s) - autophagy , apoptosis , programmed cell death , renal ischemia , hypoxia (environmental) , microbiology and biotechnology , ischemia , kidney , homeostasis , biology , chemistry , reperfusion injury , medicine , endocrinology , biochemistry , oxygen , organic chemistry

Autophagy is a dynamic catabolic process that maintains cellular homeostasis. Whether it plays a role in promoting cell survival or cell death in the process of renal ischemia/reperfusion (I/R) remains controversial, partly because renal autophagy is usually examined at a certain time point. Therefore, monitoring of the whole time course of autophagy and apoptosis may help better understand the role of autophagy in renal I/R.

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