MiR-31 Downregulation Protects Against Cardiac Ischemia/Reperfusion Injury by Targeting Protein Kinase C Epsilon (PKCe) Directly | Zendy

Yongyi Wang | Zendy; Min Men | Zendy; Wengang Yang | Zendy; Hui Zheng | Zendy; Song Xue | Zendy

Open Access

MiR-31 Downregulation Protects Against Cardiac Ischemia/Reperfusion Injury by Targeting Protein Kinase C Epsilon (PKCe) Directly

Author(s) -

Yongyi Wang,

Min Men,

Wengang Yang,

Hui Zheng,

Song Xue

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000374062

Subject(s) - downregulation and upregulation , reperfusion injury , in vivo , microrna , cardioprotection , microbiology and biotechnology , ischemia , chemistry , pharmacology , medicine , biology , gene , biochemistry

Various miRNAs have been shown to participate in cardiac ischemia/reperfusion injury (I/R). miR-31 was identified as the most strikingly upregulated miRNA after acute myocardial infarction; therefore, the underlying role and mechanism of miR-31 in cardiac I/R was investigated.

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