The Blockade of Transmembrane Cl- Flux Mitigates I/R-Induced Heart Injury via the Inhibition of Calpain Activity
Author(s) -
Jianying Zhang,
Feng Wu,
Xiaoming Gu,
Zhenxiao Jin,
Lingheng Kong,
Yuan Zhang,
JingJun Zhou,
Feng Gao
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000374018
Subject(s) - calpain , western blot , blockade , reperfusion injury , transmembrane protein , chemistry , apoptosis , ischemia , intracellular , pharmacology , flux (metallurgy) , perfusion , medicine , endocrinology , microbiology and biotechnology , biology , biochemistry , receptor , enzyme , gene , organic chemistry
The aim of this study was to determine whether calpain is involved in Cl(-)-induced myocardial ischemia/reperfusion (I/R) injury.
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