Depletion of Neutrophils Protects Against L-Arginine-Induced Acute Pancreatitis in Mice
Author(s) -
GuoLin Chen,
Feng Xu,
Jing Li,
Shiqi Lu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000374017
Subject(s) - myeloperoxidase , acute pancreatitis , pancreas , pancreatitis , intraperitoneal injection , inflammation , apoptosis , reactive oxygen species , acinar cell , infiltration (hvac) , chemistry , arginine , medicine , endocrinology , immunology , biochemistry , physics , amino acid , thermodynamics
Acute pancreatitis (AP) is an inflammatory disease characterized by acinar cell damage and inflammation of the pancreas with infiltration of leukocytes, predominantly neutrophils. We investigated whether neutrophil depletion protects against experimental AP induced by L-arginine.
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