Altered MicroRNA Expression Profiles in Activated Mast Cells Following IgE-FcεRI Cross-Linking with Antigen | Zendy

Yaoshu Teng | Zendy; Ruxin Zhang | Zendy; Hongzhi Yu | Zendy; Hong Wang | Zendy; Zhicong Hong | Zendy; Wenjie Zhuang | Zendy; Yu Huang | Zendy

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Altered MicroRNA Expression Profiles in Activated Mast Cells Following IgE-FcεRI Cross-Linking with Antigen

Author(s) -

Yaoshu Teng,

Ruxin Zhang,

Hongzhi Yu,

Hong Wang,

Zhicong Hong,

Wenjie Zhuang,

Yu Huang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000374016

Subject(s) - microrna , immunoglobulin e , biology , mast cell , immunology , immune system , microarray , bone marrow , antigen , gene expression , microbiology and biotechnology , antibody , gene , genetics

MicroRNAs (miRNAs) are critical regulators of immune responses and immunologic disorders. However, little is known about miRNA expression and function during mast cell differentiation, proliferation and activation. This study aimed to determine the miRNA expression profiles in mast cells stimulated by immunoglobulin E (IgE) and antigen and to analyze the potential functions of specific miRNAs.

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