Endothelial Cells Regulate Cardiac Myocyte Reorganisation Through β1-Integrin Signalling | Zendy

Yu Zhang | Zendy; Hai Li | Zendy; Renyue Wei | Zendy; Jing Ma | Zendy; Yanhua Zhao | Zendy; Zhengxing Lian | Zendy; Liu Z | Zendy

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Endothelial Cells Regulate Cardiac Myocyte Reorganisation Through β1-Integrin Signalling

Author(s) -

Yu Zhang,

Hai Li,

Renyue Wei,

Jing Ma,

Yanhua Zhao,

Zhengxing Lian,

Liu Z

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000373992

Subject(s) - myocyte , cardiac myocyte , paracrine signalling , integrin , microbiology and biotechnology , angiogenesis , transplantation , medicine , endothelial stem cell , endothelium , biology , receptor , biochemistry , in vitro

In normal hearts, capillaries are densely distributed throughout the myocardial tissue, and the cross-talk between myocytes and capillary endothelial cells plays a pivotal role in regulating cardiac development, maturation and function. Although previous studies have suggested a role for the endothelium in the organisation of nearby cardiomyocytes, the underlying mechanism has yet to be illustrated.

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