Quantitative Proteomic Analysis of the Metastasis-Inhibitory Mechanism of miR-193a-3p in Non-Small Cell Lung Cancer | Zendy

Wei Deng | Zendy; Mingxia Yan | Zendy; Tao Yu | Zendy; Haiyan Ge | Zendy; Hechun Lin | Zendy; Jing Li | Zendy; Ying Liu | Zendy; Geng Qin | Zendy; Miaoxin Zhu | Zendy; Lei Liu | Zendy; Xianghuo He | Zendy; Ming Yao | Zendy

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Quantitative Proteomic Analysis of the Metastasis-Inhibitory Mechanism of miR-193a-3p in Non-Small Cell Lung Cancer

Author(s) -

Wei Deng,

Mingxia Yan,

Tao Yu,

Haiyan Ge,

Hechun Lin,

Jing Li,

Ying Liu,

Geng Qin,

Miaoxin Zhu,

Lei Liu,

Xianghuo He,

Ming Yao

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000373981

Subject(s) - metastasis , mechanism (biology) , lung cancer , cancer research , microrna , cancer , inhibitory postsynaptic potential , proteomics , biology , medicine , chemistry , pathology , neuroscience , biochemistry , gene , philosophy , epistemology

microRNAs can repress the expression of target genes by destabilizing their mRNAs or by inhibiting their translation. Our previous findings suggested that miR-193a-3p inhibited the progression of NSCLC both in vitro and in vivo. However, the biological processes and molecular pathways through which this miRNA exerts its positive effects are unknown.

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