TGF-β Regulates Hepatocellular Carcinoma Progression by Inducing Treg Cell Polarization | Zendy

Yinan Shen | Zendy; Yongpeng Wei | Zendy; Zhouchong Wang | Zendy; Yingying Jing | Zendy; Haiguan He | Zendy; Jianyong Yuan | Zendy; Rong Li | Zendy; Qiudong Zhao | Zendy; Lixin Wei | Zendy; Tian Yang | Zendy; JunHua Lu | Zendy

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TGF-β Regulates Hepatocellular Carcinoma Progression by Inducing Treg Cell Polarization

Author(s) -

Yinan Shen,

Yongpeng Wei,

Zhouchong Wang,

Yingying Jing,

Haiguan He,

Jianyong Yuan,

Rong Li,

Qiudong Zhao,

Lixin Wei,

Tian Yang,

JunHua Lu

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000373976

Subject(s) - foxp3 , hepatocellular carcinoma , cancer research , transforming growth factor , tumor progression , hccs , interleukin 10 , medicine , treg cell , flow cytometry , transforming growth factor beta , cell , immunology , biology , t cell , cytokine , il 2 receptor , immune system , cancer , genetics

TGF-β plays a key role in the progression of various tumors. The main objective of our study was to investigate whether TGF-β is able to regulate N-nitrosodiethylamine (DEN)-induced hepatocellular carcinoma (HCC) progression in a mouse model by inducing Treg cell polarization.

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