Open AccessAnti-Fibrotic Effect of Plumbagin on CCl4-Lesioned Rats
Author(s) -
Yanfei Wei,
Minkui Huang,
Xuemei Liu,
Yuan Zhang,
Yue Peng,
Huang Zhen-qing,
Xue-Lin Duan,
Zhao Tie-jian
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000373974
Subject(s) - plumbagin , ccl4 , pharmacology , oxymatrine , fibrosis , hepatic stellate cell , medicine , in vivo , biology , pathology , chemistry , carbon tetrachloride , genetics , microbiology and biotechnology , organic chemistry
Our previous studies have shown that plumbagin effectively inhibits hepatic stellate cell (HSC) proliferation. Thus, plumbagin-mediated anti-fibrotic effects in vivo merit further investigation.
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