Involvement of Bim in Photofrin-Mediated Photodynamically Induced Apoptosis | Zendy

Xianwang Wang | Zendy; Xiaobing He | Zendy; Shujuan Hu | Zendy; Anbang Sun | Zendy; Chengbiao Lu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Involvement of Bim in Photofrin-Mediated Photodynamically Induced Apoptosis

Author(s) -

Xianwang Wang,

Xiaobing He,

Shujuan Hu,

Anbang Sun,

Chengbiao Lu

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000373968

Subject(s) - apoptosis , flow cytometry , gene knockdown , transfection , western blot , small hairpin rna , cancer research , confocal microscopy , microbiology and biotechnology , biology , cell culture , chemistry , biochemistry , genetics , gene

Photodynamic therapy (PDT) is a promising noninvasive technique, which has been successfully applied to the treatment of human cancers. Studies have shown that the Bcl-2 family proteins play important roles in PDT-induced apoptosis. However, whether Bcl-2-interacting mediator of cell death (Bim) is involved in photodynamic treatment remains unknown. In this study, we attempt to determine the effect of Bim on Photofrin photodynamic treatment (PPT)-induced apoptosis in human lung adenocarcinoma ASTC-a-1 cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research