Expression and Potential Role of microRNA-29b in Mouse Early Embryo Development
Author(s) -
Junqiang Zhang,
Ying Wang,
Xiaoguang Liu,
Shenglin Jiang,
Chun Zhao,
Rong Shen,
Xirong Guo,
Xiufeng Ling,
Chang Liu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000373942
Subject(s) - biology , embryo , embryogenesis , dna methylation , embryonic stem cell , blastocyst , microbiology and biotechnology , microrna , microinjection , gene expression , genetics , gene
MicroRNA-29b (miR29b) has been previously identified in early mouse embryos through miRNA microarray analysis. Recent research has indicated that miR29b participates in DNA methylation by regulating DNA methyltransferase 3a/3b (Dnmt3a/3b) expression. However, the expression pattern and biological function of miR29b in mouse preimplantation embryonic development remain unknown.
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