Open AccessRecharging Red Blood Cell Surface by Hemodialysis
Author(s) -
Katrin Kliche,
Ulrich Gerth,
Hermann Pavenstädt,
Hans Oberleithner
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000373936
Subject(s) - glycocalyx , sodium , hemodialysis , chemistry , red blood cell , dialysis , medicine , hemoglobin , endothelium , endocrinology , biochemistry , organic chemistry
Similar as in vascular endothelium the negatively charged glycocalyx of erythrocytes selectively buffers sodium. Loss of glycocalyx (i.e. loss of negative charges) leads to increased erythrocyte sodium sensitivity (ESS) quantified by a recently developed salt-blood-test (SBT). The hypothesis was tested whether a regular 4-hour hemodialysis (4h-HD) alters ESS.
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