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High Levels of Soluble Tumor Necrosis Factor Receptors 1 and 2 and Their Association with Mortality in Patients Undergoing Hemodialysis
Author(s) -
Axel C. Carlsson,
Juan Jesús Carrero,
Peter Stenvinkel,
Matteo Bottai,
Peter Bárány,
Anders Larsson,
Johan Ärnlöv
Publication year - 2015
Publication title -
cardiorenal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.661
H-Index - 21
eISSN - 1664-3828
pISSN - 1664-5502
DOI - 10.1159/000371661
Subject(s) - medicine , hemodialysis , interquartile range , end stage renal disease , dialysis , kidney disease , prospective cohort study , diabetes mellitus , proportional hazards model , cohort , endocrinology
Circulating soluble tumor necrosis factor receptors 1 and 2 (sTNFR1 and sTNFR2) are associated with chronic kidney disease (CKD) progression in patients with CKD or diabetes, and with higher mortality. However, data in patients with end-stage renal disease are scarce. Therefore, we analyzed serum levels of sTNFR1 and sTNFR2 and investigated their association with inflammatory markers and mortality in dialysis patients.

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