Influence of Pre-Storage Irradiation on the Oxidative Stress Markers, Membrane Integrity, Size and Shape of the Cold Stored Red Blood Cells
Author(s) -
Adam Antosik,
Kamila Czubak-Prowizor,
Arkadiusz Gajek,
Agnieszka Marczak,
Rafał Głowacki,
Kamila Borowczyk,
Halina Małgorzata Żbikowska
Publication year - 2015
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000371596
Subject(s) - hemolysis , oxidative stress , phosphatidylserine , chemistry , glutathione , red blood cell , andrology , echinocyte , lipid peroxidation , thiobarbituric acid , irradiation , flow cytometry , cold storage , biochemistry , microbiology and biotechnology , immunology , membrane , biology , medicine , phospholipid , physics , nuclear physics , enzyme , horticulture
To investigate the extent of oxidative damage and changes in morphology of manually isolated red blood cells (RBCs) from whole blood, cold stored (up to 20 days) in polystyrene tubes and subjected to pre-storage irradiation (50 Gy) and to compare the properties of SAGM-preserved RBCs stored under experimental conditions (polystyrene tubes) with RBCs from standard blood bag storage.
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