Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells
Author(s) -
Naruto Noma,
Masataka Asagiri,
Masatoshi Takeiri,
Saori Ohmae,
Kenji Takemoto,
Keiko Iwaisako,
Nagahiro Minato,
Mari MaedaYamamoto,
Siro Simizu,
Kazuo Umezawa
Publication year - 2015
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000371419
Subject(s) - mast cell , matrix metalloproteinase , matrigel , antigen , microbiology and biotechnology , biology , immunology , cell , cancer research , biochemistry
Stimulation with antigen and IgE is known to activate NF-κB in mast cells. In the present research, we studied the role of NF-κB on cellular migration in mast cell-like RBL-2H3 cells and bone marrow-derived mast cells (BMMCs) using the NF-κB inhibitor (-)-DHMEQ.
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