The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis | Zendy

Patricia Texeira Santana | Zendy; Cláudia F. Benjamim | Zendy; Camila Guerra Martinez | Zendy; Eleonora Kurtenbach | Zendy; Christina Maeda Takiya | Zendy; Robson CoutinhoSilva | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis

Author(s) -

Patricia Texeira Santana,

Cláudia F. Benjamim,

Camila Guerra Martinez,

Eleonora Kurtenbach,

Christina Maeda Takiya,

Robson CoutinhoSilva

Publication year - 2015

Publication title -

journal of innate immunity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.078

H-Index - 64

eISSN - 1662-8128

pISSN - 1662-811X

DOI - 10.1159/000371388

Subject(s) - proinflammatory cytokine , sepsis , medicine , immunology , cytokine , immune system , inflammation , receptor , apoptosis , biology , biochemistry

Sepsis is associated with high mortality rates in intensive care units worldwide and represents a systemic inflammatory response to infection. P2X7 is an ionotropic purine receptor with known proinflammatory activity. Here, we investigated the role of the P2X7 receptor in sepsis induced by cecal ligation and puncture (CLP).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research