Beta-Chemokine CCL15 Affects the Adhesion and Migration of Hematopoietic Progenitor Cells
Author(s) -
Rudolf Richter,
Brigitte Rüster,
Roxana Bistrian,
WolfGeorg Forssmann,
Erhard Seifried,
Reinhard Henschler
Publication year - 2014
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000370168
Subject(s) - chemokine , bone marrow , haematopoiesis , stem cell , immunology , cell adhesion , granulocyte colony stimulating factor , progenitor cell , transplantation , microbiology and biotechnology , medicine , chemistry , biology , adhesion , inflammation , organic chemistry , chemotherapy
Hematopoietic stem and progenitor cell (HPC) motility is essential for HPC transplantation. The chemokine CXCL12 is key for HPC motility. Further regulators are of interest to improve HPC transplantation and regenerative medicine. Here the impact of the human chemokine CCL15 on HPC motility was investigated.
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