Management of Electrolyte and Fluid Disorders after Brain Surgery for Pituitary/Suprasellar Tumours | Zendy

Sujata Edate | Zendy; Assunta Albanese | Zendy

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Management of Electrolyte and Fluid Disorders after Brain Surgery for Pituitary/Suprasellar Tumours

Author(s) -

Sujata Edate,

Assunta Albanese

Publication year - 2015

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000370065

Subject(s) - diabetes insipidus , medicine , polyuria , hyponatremia , antidiuretic , differential diagnosis , electrolyte disorder , syndrome of inappropriate antidiuretic hormone secretion , intensive care medicine , pediatrics , endocrinology , hormone , pathology , diabetes mellitus

Disturbances in salt and water balances are relatively common in children after brain surgeries for suprasellar and pituitary tumours, presenting diagnostic and therapeutic challenges. Although hypernatraemia associated with central diabetes insipidus is commonly encountered, it is hyponatraemia (HN) that poses more of a diagnostic dilemma. The main differential diagnoses causing HN are the syndrome of inappropriate antidiuretic hormone secretion, marked by inappropriate retention of water, and cerebral salt wasting, characterized by polyuria and natriuresis. Diagnosis and management can be even more difficult when these conditions precede or coexist with each other. These diagnostic and therapeutic dilemmas are discussed in detail in this review.

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